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The Economic Impact of Treatment Sequencing in...
Journal article

The Economic Impact of Treatment Sequencing in Chronic Lymphocytic Leukemia in Canada Using Venetoclax plus Obinutuzumab

Abstract

BACKGROUND: Bruton tyrosine kinase inhibitors (BTKis) represent an advancement in chronic lymphocytic leukemia; however, these agents are administered continuously until disease progression or unacceptable toxicity, raising concerns about their affordability. Venetoclax in combination with obinutuzumab (VO) is a fixed-duration (12-month) treatment, approved in Canada in 2020. This study estimated the total cumulative cost of different treatment …

Authors

Guinan K; Mathurin K; Lachaine J; Roc NP; Bull S-J; Tankala D; Barakat S; Manzoor BS; Hillis C; Banerji V

Journal

Cancers, Vol. 16, No. 18,

Publisher

MDPI

DOI

10.3390/cancers16183182

ISSN

2072-6694