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Mycangimycin, a Polyene Peroxide from a Mutualist...
Journal article

Mycangimycin, a Polyene Peroxide from a Mutualist Streptomyces sp.

Abstract

A mutualist actinomycete of the southern pine beetle, Dendroctonus frontalis, produces a polyene peroxide with pronounced antifungal activity. Its structure, absolute configuration, and biological activity were determined by spectral analysis, chemical modification followed by the modified Mosher method, and growth inhibitory assays, respectively.

Authors

Oh D-C; Scott JJ; Currie CR; Clardy J

Journal

Organic Letters, Vol. 11, No. 3, pp. 633–636

Publisher

American Chemical Society (ACS)

Publication Date

February 5, 2009

DOI

10.1021/ol802709x

ISSN

1523-7060