A Pilot Study of Gene Expression Modulation from...

A Pilot Study of Gene Expression Modulation from Antioxidant System of Killifish Austrolebias charrua After Exposure to Roundup Transorb®

Abstract

Roundup Transorb® (RDT) is the most popular glyphosate-based herbicide (GHB) used in agriculture, and its impact extends to non-target organisms. The annual killifish Austrolebias charrua is an endangered species endemic to southern South America and inhabits temporary ponds. This study evaluates the effects of RDT concentrations (0.065 and 5 mg/L GAE) on A. charrua exposed for 96 h. Gene expression of cat, sod2, gstα, gclc, and ucp1 was evaluated on the liver and gills. Highlighting that even at low concentrations permitted by Brazilian legislation, the RDT can have adverse effects on A. charrua.

Authors

Gonçalves NM; Silveira TLR; Martins AWS; Dellagostin EN; Blödorn EB; Nunes LS; Domingues WB; Salvi LC; Costa PG; Bianchini A

Journal

Bulletin of Environmental Contamination and Toxicology, Vol. 113, No. 2,

Publisher

Springer Nature

Publication Date

August 1, 2024

DOI

10.1007/s00128-024-03930-w

ISSN

0007-4861

Associated Experts

Adalto Bianchini

Adjunct Professor, Faculty of Science

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