Chemosensitization and brachytherapy in palliation of advanced esophageal cancer

Brachytherapy has been shown to be effective for palliating advanced esophageal cancer. This report examines the role of brachytherapy and chemosensitization in a prospective randomized study. A total of 200 patients with inoperable, locally advanced esophageal cancer were randomized into four treatment groups. Chemosensitization was given with 5-fluorouracil 500 mg/m² as a continuous infusion for five days. Group A received high dose rate …