Journal article
The lncRNAMALAT1-WTAP axis: a novel layer of EMT regulation in hypoxic triple-negative breast cancer
Abstract
Early metastatic disease development is one characteristic that defines triple-negative breast cancer (TNBC) as the most aggressive breast cancer (BC) subtype. Numerous studies have identified long non-coding RNAs (lncRNA) as critical players in regulating tumor progression and metastasis formation. Here, we show that MALAT1, a long non-coding RNA known to promote various features of BC malignancy, such as migration and neo angiogenesis, …
Authors
Dragonetti M; Turco C; Benedetti A; Goeman F; Forcato M; Scalera S; Allegretti M; Esposito G; Fazi F; Blandino G
Journal
Cell Death Discovery, Vol. 10, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41420-024-02058-4
ISSN
2058-7716