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Illuminating cortactin structure and function at...
Journal article

Illuminating cortactin structure and function at actin filament branches

Abstract

Stabilization of a branch structure would intuitively suggest a direct connection between trunk and bough, but in actin filament networks, cortactin clamps the branching Arp2/3 complex to the daughter filament. This has fundamental consequences for mechanistic understanding of actin branch turnover and cortactin biology.

Authors

Rottner K; Bieling P

Journal

Nature Structural & Molecular Biology, Vol. 31, No. 5, pp. 739–741

Publisher

Springer Nature

Publication Date

May 2024

DOI

10.1038/s41594-024-01297-4

ISSN

1545-9993