Membrane-Based Micro-Volume Dialysis Method for Rapid and High-Throughput Protein Crystallization

Protein crystallization techniques are very important in drug development. This paper discusses a membrane-based micro-volume dialysis method suitable for rapid and high-throughput protein crystallization. A droplet of protein solution was deposited on the membrane surface in a micro-volume dialysis device. Crystallizing agents could be added to the protein solution either directly or through the membrane. The crystallization process could …