Journal article
Increased Cell Proliferations and Neurogenesis in the Hippocampal Dentate Gyrus of Ahnak Deficient Mice
Abstract
Expression of the giant protein Ahnak has been reported in endothelial cells of the blood brain barrier and in non-neuronal cells including myelinating Schwann cells. However, the function of Ahnak in neurogenesis has not been determined. In the present study, we report for the first time the effects of Ahnak on adult hippocampal neurogenesis using Ahnak−/− mice. Proliferating cells were labeled with BrdU for a 30-day period before sacrifice. …
Authors
Shin JH; Kim YN; Kim IY; Choi D-H; Yi SS; Seong JK
Journal
Neurochemical Research, Vol. 40, No. 7, pp. 1457–1462
Publisher
Springer Nature
Publication Date
July 2015
DOI
10.1007/s11064-015-1615-0
ISSN
0364-3190