Journal article
Inflammatory pathways in malaria infection: TLRs share the stage with other components of innate immunity
Abstract
Severe forms of malaria infection claim over 1 million lives annually. One aspect of severe malaria pathogenesis is an excessive or dysregulated inflammatory response to infection. With the characterization of Toll-like receptors (TLRs), which initiate inflammation upon detection of microbial products, involvement of TLRs in the host response to malaria has undergone intense investigation. While TLRs appear to mediate inflammation in malaria …
Authors
Erdman LK; Finney CAM; Liles WC; Kain KC
Journal
Molecular and Biochemical Parasitology, Vol. 162, No. 2, pp. 105–111
Publisher
Elsevier
Publication Date
12 2008
DOI
10.1016/j.molbiopara.2008.08.006
ISSN
0166-6851