Journal article
Expanded vacuum-stable gels for multiplexed high-resolution spatial histopathology
Abstract
Cellular organization and functions encompass multiple scales in vivo. Emerging high-plex imaging technologies are limited in resolving subcellular biomolecular features. Expansion Microscopy (ExM) and related techniques physically expand samples for enhanced spatial resolution, but are challenging to be combined with high-plex imaging technologies to enable integrative multiscaled tissue biology insights. Here, we introduce Expand and comPRESS …
Authors
Bai Y; Zhu B; Oliveria J-P; Cannon BJ; Feyaerts D; Bosse M; Vijayaragavan K; Greenwald NF; Phillips D; Schürch CM
Journal
Nature Communications, Vol. 14, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41467-023-39616-w
ISSN
2041-1723