Journal article
Efficacy and safety of a bolus of half-dose r-SAK prior to primary PCI in ST-elevation myocardial infarction: Rationale and design of the OPTIMA-6 trial
Abstract
BACKGROUND: Time to reperfusion is the key to the treatment of patients with ST-elevation myocardial infarction (STEMI). It is uncertain whether adjunctive thrombolytic therapy combined with contemporary antiplatelet agent ticagrelor improves outcomes as administered prior to primary percutaneous coronary intervention (PCI) expected to be performed within 120 minutes.
METHODS: OPTIMA-6 is a multicenter, randomized, double-blind, …
Authors
Li C; Eikelboom JW; Zhong Z; Zhang X; Liu K; Zhu L; Yang N; Chen X; Wang X; Zhao X
Journal
American Heart Journal, Vol. 265, , pp. 31–39
Publisher
Elsevier
Publication Date
November 2023
DOI
10.1016/j.ahj.2023.06.012
ISSN
0002-8703