Journal article
Hyperpolarized 3He and 129Xe MRI: Differences in asthma before bronchodilation
Abstract
PURPOSE: To compare hyperpolarized helium-3 ((3) He) and xenon-129 ((129) Xe) MRI in asthmatics before and after salbutamol inhalation.
MATERIALS AND METHODS: Seven asthmatics provided written informed consent and underwent spirometry, plethysmography, and MRI before and after salbutamol inhalation. (3) He and (129) Xe ventilation defect percent (VDP) and ventilation coefficient of variation (COV) were measured. To characterize the airways …
Authors
Svenningsen S; Kirby M; Starr D; Leary D; Wheatley A; Maksym GN; McCormack DG; Parraga G
Journal
Journal of Magnetic Resonance Imaging, Vol. 38, No. 6, pp. 1521–1530
Publisher
Wiley
Publication Date
December 2013
DOI
10.1002/jmri.24111
ISSN
1053-1807