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Effect of Canagliflozin on Heart Failure...
Journal article

Effect of Canagliflozin on Heart Failure Hospitalization in Diabetes According to Baseline Heart Failure Risk

Abstract

BACKGROUND: In the CANVAS (Canagliflozin Cardiovascular Assessment Study) program, canagliflozin reduced the risk of heart failure (HF) hospitalization among individuals with type 2 diabetes mellitus (T2DM). OBJECTIVES: The purpose of this study was to evaluate heterogeneity in absolute and relative treatment effects of canagliflozin on HF hospitalization according to baseline HF risk as assessed by diabetes-specific HF risk scores (WATCH-DM …

Authors

Khan MS; Segar MW; Usman MS; Patel KV; Van Spall HGC; DeVore AD; Vaduganathan M; Lam CSP; Zannad F; Verma S

Journal

JACC Heart Failure, Vol. 11, No. 7, pp. 825–835

Publisher

Elsevier

Publication Date

July 2023

DOI

10.1016/j.jchf.2023.03.025

ISSN

2213-1779