Preprint
Stroke genetics informs drug discovery and risk prediction across ancestries
Abstract
Previous genome-wide association studies (GWAS) of stroke, the second leading cause of death, have been conducted in populations of predominantly European ancestry.1,2 We undertook cross-ancestry GWAS meta-analyses of stroke and its subtypes in 110,182 stroke patients (33% non-European) and 1,503,898 control individuals of five ancestries from population- and clinic-based studies, nearly doubling the number of cases in previous stroke GWAS. We …
Authors
Debette S; Mishra A; Malik R; Hachiya T; Jürgenson T; Namba S; Koido M; Grand QL; Kamanu F; Shi M
DOI
10.21203/rs.3.rs-1175817/v1
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