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Preprint

Patient-important Outcomes Reported in Clinical Studies of Pharmacologic Treatments for COVID-19: A Protocol of a Meta-epidemiological Study

Abstract

Background: The coronavirus disease 19 (covid-19) pandemic has underscored the need to expedite clinical research, which may lead investigators to shift away from measuring patient-important outcomes (PIOs), limiting research applicability. We aim to describe the extent to which randomized controlled trials (RCTs) of covid-19 therapies will determine PIOs.

Methods: We will perform a meta-epidemiological study of RCTs that included people at …

Authors

Jimenez-Mora MA; Varela AR; Meneses-Echavez JF; Bidonde J; Angarita-Fonseca A; Siemieniuk RA; Zeraatkar D; Bartoszko J; Brignardello-Petersen R; Honarmand K

DOI

10.21203/rs.3.rs-107409/v1

Preprint server

Research Square