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Stereotactic Body Radiotherapy (SBRT) Versus...
Preprint

Stereotactic Body Radiotherapy (SBRT) Versus Conventional Palliative Radiotherapy (CRT) for Patients With Painful Spinal Metastases: A Phase 3, Randomized Controlled Trial

Abstract

Background: Conventional external beam radiation (CRT) is standard palliative treatment for spinal metastases; however, complete response rates for pain are low. Stereotactic body radiotherapy (SBRT) delivers high dose ablative radiotherapy. We aimed to compare complete response rates (CR) for pain between SBRT and CRT to painful spinal metastases. Methods: We did this multicenter, phase 2/3, randomised controlled trial in 13 hospitals in …

Authors

Sahgal A; Myrehaug SD; Siva S; Masucci GL; Maralani PJ; Brundage M; Butler J; Chow E; Fehlings MG; Foote M

Publication date

January 1, 2021

DOI

10.2139/ssrn.3783795

Preprint server

SSRN Electronic Journal