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Kinetic Analysis of Dominant Intraprostatic Lesion...
Preprint

Kinetic Analysis of Dominant Intraprostatic Lesion of Prostate Cancer Using Quantitative Dynamic [18F]DCFPyL-PET: Comparison to [18F]fluorocholine-PET

Abstract

Purpose Identification of the dominant intraprostatic lesion(s) (DILs) can facilitate diagnosis and treatment by targeting biologically significant intra-prostatic foci. A PSMA ligand, [18F]DCFPyL (2-(3-{1-carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid), is better than choline-based [18F]FCH (Fluorocholine) in detecting and localizing DIL because of higher tumour contrast, particularly when imaging is …

Authors

Yang D-M; Li F; Bauman G; Chin J; Pautler S; Moussa M; Rachinsky I; Valliant J; Lee T-Y

DOI

10.21203/rs.3.rs-35928/v2

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