Adaptation in a fibronectin binding autolysin of Staphylococcus saprophyticus

Abstract Human-pathogenic bacteria are found in a variety of niches, including free-living, zoonotic, and microbiome environments. Identifying bacterial adaptions that enable invasive disease is an important means of gaining insight into the molecular basis of pathogenesis and understanding pathogen emergence. Staphylococcus saprophyticus , a leading cause of urinary tract infections, can be found in the environment, food, animals, and the …