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Differentiated extracts from freshwater and...
Preprint

Differentiated extracts from freshwater and terrestrial mollusks inhibit virulence factor production in Cryptococcus neoformans

Abstract

The human fungal pathogen, Cryptococcus neoformans, is responsible for deadly infections among immunocompromised individuals with the evolution of antifungal resistance driving the need for discovery of new compounds that inhibit fungal virulence factors, rather than kill the pathogen. Recently, exploration into natural sources (e.g., plants, invertebrates, microbes) of antifungal agents has garnered attention by integrating a One Health …

Authors

Gutierrez-Gongora D; Raouf-Alkadhimi F; Prosser RS; Geddes-McAlister J

DOI

10.21203/rs.3.rs-2399634/v1

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