Journal article
Effects of liver metastases on efficacy of immune checkpoint blockade in treatment refractory, metastatic colorectal cancer (CRC): CCTG CO.26.
Abstract
3600
Background: Immune checkpoint blockade has limited activity in microsatellite-stable (MSS) or mis-match repair proficient (pMMR) CRC. Recent findings suggest that immunotherapy efficacy may be modulated by the presence of liver metastases. We conducted a retrospective analysis of the Canadian Cancer Trials Group (CCTG) CO.26 study to investigate the relationship between the presence of liver metastases and activity of …
Authors
Chen EX; Loree JM; Tu D; O'Callaghan CJ; Kennecke HF; Jonker DJ; Chaudhary A; Colwell B; Harb M; Aucoin N
Journal
Journal of Clinical Oncology, Vol. 40, No. 16_suppl, pp. 3600–3600
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
June 1, 2022
DOI
10.1200/jco.2022.40.16_suppl.3600
ISSN
0732-183X