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Accelerated Wound Healing by In vivo Application...
Journal article

Accelerated Wound Healing by In vivo Application of Keratinocytes Overexpressing KGF

Abstract

Epidermal regeneration is a complex process, strongly influenced by growth factors, including keratinocyte growth factor (KGF). The objective of this study was to establish immortalized HaCaT keratinocytes and KMST-6-fibroblasts stably expressing KGF. Transfection efficiency, genomic integration, and functionality of the transgene were determined by ELISA and PCR, and KGF-expressing clones were selected using an air-liquid interface test …

Authors

Kopp J; Wang GY; Kulmburg P; Schultze-Mosgau S; Huan JN; Ying K; Seyhan H; Jeschke MD; Kneser U; Bach AD

Journal

Molecular Therapy, Vol. 10, No. 1, pp. 86–96

Publisher

Elsevier

Publication Date

7 2004

DOI

10.1016/j.ymthe.2004.04.016

ISSN

1525-0016