Journal article
CHARACTERIZATION OF THE INFLAMMATORY RESPONSE DURING ACUTE AND POST-ACUTE PHASES AFTER SEVERE BURN
Abstract
Severe burn causes a pronounced hypermetabolic response characterized by catabolism and extensive protein wasting. We recently found that this hypermetabolic state is driven by a severe inflammatory response. We characterized in detail the kinetics of serum levels of a panel of cytokines in a rat model, which may serve as reference for the development of therapeutic interventions applicable to humans. Male Sprague-Dawley rats (n = 8) received a …
Authors
Gauglitz GG; Song J; Herndon DN; Finnerty CC; Boehning D; Barral JM; Jeschke MG
Journal
Shock, Vol. 30, No. 5, pp. 503–507
Publisher
Wolters Kluwer
Publication Date
November 2008
DOI
10.1097/shk.0b013e31816e3373
ISSN
1073-2322