Journal article
Less is more: Antibiotics at the beginning of life
Abstract
Antibiotic exposure at the beginning of life can lead to increased antimicrobial resistance and perturbations of the developing microbiome. Early-life microbiome disruption increases the risks of developing chronic diseases later in life. Fear of missing evolving neonatal sepsis is the key driver for antibiotic overtreatment early in life. Bias (a systemic deviation towards overtreatment) and noise (a random scatter) affect the decision-making …
Authors
Stocker M; Klingenberg C; Navér L; Nordberg V; Berardi A; el Helou S; Fusch G; Bliss JM; Lehnick D; Dimopoulou V
Journal
Nature Communications, Vol. 14, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41467-023-38156-7
ISSN
2041-1723