Journal article
Apoptotic cell death in disease—Current understanding of the NCCD 2023
Abstract
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this process not only to (post-)embryonic development and adult tissue homeostasis, but also to the etiology of multiple human disorders. Consistent with this notion, while defects in the molecular …
Authors
Vitale I; Pietrocola F; Guilbaud E; Aaronson SA; Abrams JM; Adam D; Agostini M; Agostinis P; Alnemri ES; Altucci L
Journal
Cell Death & Differentiation, Vol. 30, No. 5, pp. 1097–1154
Publisher
Springer Nature
Publication Date
5 2023
DOI
10.1038/s41418-023-01153-w
ISSN
1350-9047