Journal article
665 Transcriptional landscape of tumor-reactive TIL in lung cancer and melanoma
Abstract
Melanoma and lung cancers have two of the highest response rates to immune checkpoint inhibitors (ICIs).1 However, patients may respond unpredictably, partly due to heterogeneity in the quantity and quality of tumor-specific T cells. In this study, we performed an integrated transcriptomic analysis of anti-tumor CD8+ TIL from non-small cell lung cancer (NSCLC) and melanoma. Our goal was to study the global transcriptomic landscape of …
Authors
Zhang J; Caushi J; Zhang B; Ji Z; Li T; Ji H; Pardoll A; Smith K
Journal
Journal for ImmunoTherapy of Cancer, Vol. 9, No. Suppl 2, pp. a693–a693
Publisher
BMJ
Publication Date
11 2021
DOI
10.1136/jitc-2021-sitc2021.665
ISSN
2051-1426