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Journal article

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support

Abstract

BACKGROUND: Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and management of alloimmunization, delayed hemolytic transfusion reactions (DHTRs), and iron overload may improve outcomes. OBJECTIVE: Our objective was to develop evidence-based guidelines to …

Authors

Chou ST; Alsawas M; Fasano RM; Field JJ; Hendrickson JE; Howard J; Kameka M; Kwiatkowski JL; Pirenne F; Shi PA

Journal

Blood Advances, Vol. 4, No. 2, pp. 327–355

Publisher

American Society of Hematology

Publication Date

January 27, 2020

DOI

10.1182/bloodadvances.2019001143

ISSN

2473-9529