Animal Models for Peritoneal Dialysis Research

The concept of peritoneal dialysis as a therapeutic modality for end stage renal disease was first demonstrated by Putnam in 1923 in a canine animal model [1]. Over the past 30 years, as peritoneal dialysis has been increasingly used and modified as a therapy for renal failure, animal models have been used to understand the physiology of the peritoneum membrane, and to test new therapeutic interventions to improve the outcomes of patients …