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Myofibroblasts in Nasal Polyposis: Regulation by...
Journal article

Myofibroblasts in Nasal Polyposis: Regulation by Topical Steroids

Abstract

OBJECTIVES: To compare numbers of myofibroblasts, a fibroblast phenotype associated with chronically inflamed tissue, in nasal polyp tissues from untreated and corticosteroid‐treated subjects. To study whether corticosteroids can directly affect myofibroblast differentiation in vitro. PATIENTS AND METHODS: Immunolocalization of alpha‐smooth muscle actin (alpha‐SMA) as a marker of myofibroblast differentiation, vimentin and transforming growth …

Authors

Tremblay GM; Nonaka M; Särnstrand B; Dolovich J; Gauldie J; Jordana M

Journal

Canadian Respiratory Journal, Vol. 4, No. 4, pp. 205–210

Publisher

Wiley

Publication Date

1 1997

DOI

10.1155/1997/901819

ISSN

1198-2241