Journal article
Time-dependent optical spectroscopy and imaging for biomedical applications
Abstract
The application of optical spectroscopy and imaging in living tissue is complicated by multiple scattering of light. In spectroscopy, this scattering causes uncertainty in the pathlength traveled by photons in the tissue, while images suffer reduced resolution and contrast. Picosecond light sources and fast detectors have made it possible to address these problems by direct measurement of the photon time-of-flight. Diffusion models of light …
Authors
Wilson BC; Sevick EM; Patterson MS; Chance B
Journal
Proceedings of the IEEE, Vol. 80, No. 6, pp. 918–930
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Publication Date
June 1992
DOI
10.1109/5.149454
ISSN
0018-9219