A173 LACK OF EXPERIMENTAL REPRODUCIBILITY IN PRECLINICAL RESEARCH: FOCUS ON DIETARY CONTENT OF FERMENTABLE CARBOHYDRATE (FODMAPS) IN STANDARD RODENT CHOWS

The Canadian Institute of Health Research (CIHR) and other scientific organizations have raised concern about the variability and lack of reproducibility of animal experimental results between laboratories. This concern includes studies investigating the microbiota, their metabolites and their impact on the host. Factors such as environment, stress, and sex have been identified as possible contributors, whereas composition of the regular diet, …