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Methodology and design of platform trials: a...
Journal article

Methodology and design of platform trials: a meta-epidemiological study

Abstract

OBJECTIVES: Adaptive platforms allow for the evaluation of multiple interventions at a lower cost and have been growing in popularity, especially during the COVID-19 pandemic. The objective of this review is to summarize published platform trials, examine specific methodological design features among these studies, and hopefully aid readers in the evaluation and interpretation of platform trial results. METHODS: We performed a systematic review …

Authors

Pitre T; Cheng S; Cusano E; Khan N; Mikhail D; Leung G; Vernooij RWM; Yarnell CJ; Goligher E; Murthy S

Journal

Journal of Clinical Epidemiology, Vol. 157, , pp. 1–12

Publisher

Elsevier

Publication Date

5 2023

DOI

10.1016/j.jclinepi.2023.02.010

ISSN

0895-4356