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Orchestrating Binding Interactions and the...
Journal article

Orchestrating Binding Interactions and the Emergence of Avidity Driven Therapeutics

Abstract

Multiple carbohydrate ligands are arranged within a single therapeutic agent to achieve significant increases in apparent binding affinity or “avidity” for a target lectin receptor.

Authors

Kapcan E; Lake BPM; Rullo AF

Journal

ACS Central Science, Vol. 9, No. 4, pp. 586–589

Publisher

American Chemical Society (ACS)

Publication Date

April 26, 2023

DOI

10.1021/acscentsci.3c00242

ISSN

2374-7943