Journal article
A novel assay for improved detection of sputum periostin in patients with asthma
Abstract
BACKGROUND: Serum periostin associates with type-2 inflammation in asthmatic airways, but also reflects whole body periostin levels originating from multiple sources. Less is known about sputum periostin as a biomarker in asthma as detection levels are low using currently available periostin assays. We aimed to investigate detection of sputum periostin using ELISA assays targeting different periostin epitopes and relate levels to clinical …
Authors
Ono J; Takai M; Kamei A; Ohta S; Nair P; Izuhara K; Dahlén S-E; James A; consortium OBOTB
Journal
PLOS ONE, Vol. 18, No. 2,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0281356
ISSN
1932-6203