Journal article
Dysregulation of neuroendocrine crossroads: Depression, orcadian rhythms and the retina — A hypothesis
Abstract
The pathophysiology of depression and the mechanism of action of lithium and other antidepressant drugs involve alterations in circadian rhythms. These include changes in both the intrinsic rhythm of circadian oscillators and in the sensitivity of the retina to LIGHT. The retina in humans is the only photoreceptor for circadian entrainment. The retinal-hypothalamic-pineal axis is the essential pathway for neuronal entrainment of rhythms which …
Authors
Steiner; Werstiuk ES; Seggie J
Journal
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 11, No. 2-3, pp. 267–278
Publisher
Elsevier
Publication Date
January 1987
DOI
10.1016/0278-5846(87)90070-4
ISSN
0278-5846