Journal article
Cross-over study comparing effects of treatment with an angiotensin converting enzyme inhibitor and an angiotensin II type 1 receptor antagonist on cardiovascular changes in hypertension
Abstract
OBJECTIVE: To compare the blood-pressure-lowering effects of an angiotensin converting enzyme inhibitor, perindopril, with those of an angiotensin II type 1 receptor antagonist, L-158,809, for adult spontaneously hypertensive rats.
DESIGN: A cross-over design was used, to treat adult spontaneously hypertensive rats with one drug for 10 weeks, and then with the other for 5 weeks.
Authors
Gillies LK; Werstiuk ES; Lee RMKW
Journal
Journal of Hypertension, Vol. 16, No. 4, pp. 477–486
Publisher
Wolters Kluwer
Publication Date
April 1998
DOI
10.1097/00004872-199816040-00009
ISSN
0263-6352