Journal article
Epinephrine in Out-of-Hospital Cardiac Arrest A Network Meta-analysis and Subgroup Analyses of Shockable and Nonshockable Rhythms
Abstract
BACKGROUND: Epinephrine is the most commonly used drug in out-of-hospital cardiac arrest (OHCA) resuscitation, but evidence supporting its efficacy is mixed.
RESEARCH QUESTION: What are the comparative efficacy and safety of standard dose epinephrine, high-dose epinephrine, epinephrine plus vasopressin, and placebo or no treatment in improving outcomes after OHCA?
Authors
Fernando SM; Mathew R; Sadeghirad B; Rochwerg B; Hibbert B; Munshi L; Fan E; Brodie D; Di Santo P; Tran A
Journal
CHEST Journal, Vol. 164, No. 2, pp. 381–393
Publisher
Elsevier
Publication Date
August 2023
DOI
10.1016/j.chest.2023.01.033
ISSN
0012-3692