Meta-Analysis of Combined Therapy with Angiotensin Receptor Antagonists versus ACE Inhibitors Alone in Patients with Heart Failure

Abstract

BACKGROUND: There is insufficient evidence whether the benefit of adding angiotensin II receptor blockers (ARBs) to angiotensin-converting enzyme (ACE) inhibitors outweighs the increased risk of adverse effects in patients with heart failure. METHODOLOGY/PRINCIPAL FINDINGS: Two independent reviewers searched and abstracted randomized controlled trials of ARBs and ACE inhibitors compared to ACE inhibitor therapy alone in patients with heart …

Authors

Kuenzli A; Bucher HC; Anand I; Arutiunov G; Kum LC; McKelvie R; Afzal R; White M; Nordmann AJ

Journal

PLOS ONE, Vol. 5, No. 4,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0009946

ISSN

1932-6203

Associated Experts

Robert McKelvie

Professor Emeritus, Faculty of Health Sciences

Visit profile

Labels