Journal article
Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia
Abstract
Lungs are the central organ affected and targeted by Mycobacterium tuberculosis and immune processes in the lung are of critical importance in the pathogenesis of tuberculosis. A major lung defense against invading pathogens is provided by surfactant protein A, a multi-chain protein encoded by the SFTPA1 and SFTPA2 genes. Here, we investigated polymorphisms in the SFTPA1 and SFTPA2 genes for association with tuberculosis in 181 Ethiopian …
Authors
Malik S; Greenwood CMT; Eguale T; Kifle A; Beyene J; Habte A; Tadesse A; Gebrexabher H; Britton S; Schurr E
Journal
Human Genetics, Vol. 118, No. 6, pp. 752–759
Publisher
Springer Nature
Publication Date
February 2006
DOI
10.1007/s00439-005-0092-y
ISSN
0340-6717