Journal article
In vivo TESTS OF THE CONCEPT OF PHOTODYNAMIC THRESHOLD DOSE IN NORMAL RAT LIVER PHOTOSENSITIZED BY ALUMINUM CHLOROSULPHONATED PHTHALOCYANINE
Abstract
In its simplest form, the photodynamic therapy (PDT) threshold dose model states that tissue necrosis due to PDT will occur if the number of photons absorbed by the photosensitizer per unit volume of tissue exceeds a critical value. This threshold is given by the product of photon fluence, photosensitizer concentration and specific absorption coefficient. To test the validity of this concept for PDT of normal rat liver sensitized with aluminum …
Authors
Patterson MS; Wilson BC; Graff R
Journal
Photochemistry and Photobiology, Vol. 51, No. 3, pp. 343–349
Publisher
Wiley
Publication Date
March 1990
DOI
10.1111/j.1751-1097.1990.tb01720.x
ISSN
0031-8655