Journal article
Experimental tests of the feasibility of singlet oxygen luminescence monitoring in vivo during photodynamic therapy
Abstract
Singlet oxygen (1O2) is thought to be the cytotoxic agent in photodynamic therapy (PDT) with current photosensitizers. Direct monitoring of 1O2 concentration in vivo would be a valuable tool in studying biological response. Attempts were made to measure 1O2 IR luminescence during PDT of cell suspensions and two murine tumour models using the photosensitizers Photofrin II and aluminium chlorosulphonated phthalocyanine. Instrumentation was …
Authors
Patterson MS; Madsen SJ; Wilson BC
Journal
Journal of Photochemistry and Photobiology B Biology, Vol. 5, No. 1, pp. 69–84
Publisher
Elsevier
Publication Date
April 1990
DOI
10.1016/1011-1344(90)85006-i
ISSN
1011-1344