Imaging of Photodynamically Generated Singlet...

Imaging of Photodynamically Generated Singlet Oxygen Luminescence In Vivo

Abstract

We describe a novel scanning-laser system for imaging type-II photodynamically generated singlet oxygen (1O21g) luminescence and demonstrate it in vivo in an intradermal tumor model in mice. We verify the strong oxygen-dependence of the signal and show that the images are near the practical resolution limit.

Authors

Niedre MJ; Patterson MS; Giles A; Wilson BC

Journal

Photochemistry and Photobiology, Vol. 81, No. 4, pp. 941–943

Publisher

Wiley

Publication Date

July 1, 2005

DOI

10.1562/2005-03-15-tsn-462r.1

ISSN

0031-8655

Associated Experts

Mike Patterson

Professor, Faculty of Health Sciences

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