Journal article
Monitoring oxygen concentration during photodynamic therapy using prompt photosensitizer fluorescence
Abstract
A novel technique is described that uses either time-resolved or steady state prompt photosensitizer fluorescence to measure local oxygen concentration. Solution experiments conducted with Al(III) phthalocyanine chloride tetrasulfonic acid confirmed that the steady state fluorescence signal is dependent on the oxygen concentration and fluence rate. A relationship between prompt sensitizer fluorescence and sensitizer triplet quenching efficiency …
Authors
Weston MA; Patterson MS
Journal
Physics in Medicine and Biology, Vol. 58, No. 20, pp. 7039–7059
Publisher
IOP Publishing
Publication Date
October 21, 2013
DOI
10.1088/0031-9155/58/20/7039
ISSN
0031-9155