Journal article
A Preliminary Pharmacogenetic Investigation of Adverse Events From Topiramate in Heavy Drinkers
Abstract
Topiramate, an anticonvulsant medication, is an efficacious treatment for alcohol dependence. To date, little is known about genetic moderators of side effects from topiramate. The objective of this study was to examine 3 single nucleotide polymorphisms (SNPs) of the glutamate receptor GluR5 gene (GRIK1) as predictors of topiramate-induced side effects in the context of a laboratory study of topiramate. Heavy drinkers (n=51, 19 women and 32 …
Authors
Ray LA; Miranda R; MacKillop J; McGeary J; Tidey JW; Rohsenow DJ; Gwaltney C; Swift RW; Monti PM
Journal
Experimental and Clinical Psychopharmacology, Vol. 17, No. 2, pp. 122–129
Publisher
American Psychological Association (APA)
Publication Date
April 2009
DOI
10.1037/a0015700
ISSN
1064-1297