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Neutron and cobalt-60 gamma irradiation produce...
Journal article

Neutron and cobalt-60 gamma irradiation produce similar changes in DNA supercoiling.

Abstract

The effects of 60Co gamma-ray and d(20 MeV)Be neutron irradiation on DNA supercoiling have been studied using a nucleoid rewinding technique. Irradiation of viable CHO AA8 cells on ice with from 4 to 25 Gy of either radiation produced a similar resistance to rewinding of nuclear supercoils after treatment with ethidium bromide. The restitution from the effects of 12 Gy of either radiation was also similar, leaving no detectable residual damage. …

Authors

Vaughan AT; Gordon DJ; Chettle DR; Green S

Journal

Radiation Research, Vol. 127, No. 1, pp. 19–23

Publisher

JSTOR

Publication Date

July 1991

DOI

10.2307/3578083

ISSN

0033-7587