Prevention of preeclampsia with aspirin: a systematic review of guidelines and evaluation of recommendation evidence

Objectives Preeclampsia is a major cause of maternal and infant mortality and morbidity. Randomized evidence has shown aspirin significantly reduces preterm preeclampsia and perinatal death. Our objectives were to systematically review clinical practice guidelines and other statements to evaluate recommendations on aspirin for preeclampsia prevention. Methods Ten databases were searched for clinical practice guidelines and other statements …