Journal article
A288 DISTINCT ROLES IN INNATE HOST DEFENSE AND SUSCEPTIBILITY TO COLONIC INJURY IN MUC2 MUCIN DEFICIENT AND SUFFICIENT MICROBIOTA
Abstract
The intestinal epithelium is covered with a thick viscous MUC2 mucin bilayer that acts as a protective barrier and is the habitat for 1014 microorganisms that form the microbiota. Even though disruption of colonic mucus and alterations in microbial composition are intimately linked to gastrointestinal health and disease, their distinct contribution in the pathogenesis of colitis is not well understood. To interrogate the impact of alterations …
Authors
Leon-Coria A; Moreau F; Workentine M; Surette M; Chadee K
Journal
Journal of the Canadian Association of Gastroenterology, Vol. 1, No. suppl_1, pp. 499–500
Publisher
Oxford University Press (OUP)
Publication Date
March 1, 2018
DOI
10.1093/jcag/gwy008.289
ISSN
2515-2084