Journal article
Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke
Abstract
OBJECTIVE: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms.
METHODS: We first sought to identify genetic associations with white matter hyperintensities in a stroke population, and then examined whether genetic …
Authors
Traylor M; Zhang CR; Adib-Samii P; Devan WJ; Parsons OE; Lanfranconi S; Gregory S; Cloonan L; Falcone GJ; Radmanesh F
Journal
Neurology, Vol. 86, No. 2, pp. 146–153
Publisher
Wolters Kluwer
Publication Date
January 12, 2016
DOI
10.1212/wnl.0000000000002263
ISSN
0028-3878