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Rationale, Design, and the Baseline...
Journal article

Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Study†

Abstract

BACKGROUND: The genetics of rheumatic heart disease (RHDGen) Network was developed to assist the discovery and validation of genetic variations and biomarkers of risk for rheumatic heart disease (RHD) in continental Africans, as a part of the global fight to control and eradicate rheumatic fever/RHD. Thus, we describe the rationale and design of the RHDGen study, comprising participants from 8 African countries. METHODS: RHDGen screened …

Authors

Machipisa T; Chishala C; Shaboodien G; Zühlke LJ; Muhamed B; Pandie S; de Vries J; Laing N; Joachim A; Daniels R

Journal

Circulation Genomic and Precision Medicine, Vol. 16, No. 1, pp. e003641–e003641

Publisher

Wolters Kluwer

Publication Date

February 2023

DOI

10.1161/circgen.121.003641

ISSN

1942-325X