Journal article
Abstract 559: FTY720 Protects Against Diet Induced Coronary Artery Disease and Myocardial Infarction in Diabetic SR-B1-/- ApoE-Hypomorphic Mice
Abstract
Background: Epidemiological studies have established diabetes as a risk factor for the development of cardiovascular diseases. Increased development of aortic atherosclerosis has been shown in diabetic animal models, but the effect on coronary artery (CA) disease is less clear. Conventional mouse models of atherosclerosis do not reproducibly develop CA atherosclerosis. SR-B1-/- apoE-hypomorphic mice develop increased aortic sinus …
Authors
Gonzalez-Jara LA; Werstuck G; Trigatti B
Journal
Arteriosclerosis Thrombosis and Vascular Biology, Vol. 35, No. suppl_1,
Publisher
Wolters Kluwer
Publication Date
5 2015
DOI
10.1161/atvb.35.suppl_1.559
ISSN
1079-5642