Journal article
Aqueous skin antisepsis before surgical fixation of open fractures (Aqueous-PREP): a multiple-period, cluster-randomised, crossover trial
Abstract
BACKGROUND: Chlorhexidine skin antisepsis is frequently recommended for most surgical procedures; however, it is unclear if these recommendations should apply to surgery involving traumatic contaminated wounds where povidone-iodine has previously been preferred. We aimed to compare the effect of aqueous 10% povidone-iodine versus aqueous 4% chlorhexidine gluconate on the risk of surgical site infection in patients who required surgery for an …
Authors
Slobogean GP; Sprague S; Wells JL; Bhandari M; Harris AD; Mullins CD; Thabane L; Wood A; Della Rocca GJ; Hebden JN
Journal
The Lancet, Vol. 400, No. 10360, pp. 1334–1344
Publisher
Elsevier
Publication Date
October 2022
DOI
10.1016/s0140-6736(22)01652-x
ISSN
0140-6736